Different user input suggestions/choises, like confirm, deny, etc. are by default on the right side of the screen where you have the three buttons for all of these actions.
When you change your Pebble to left handed mode, the location of the input suggestions/selections are still on the right side, even though the buttons are on the left side of the screen.
Please align the location of selection on screen with the actual button location depending on whether you use left handed mode or not.
Thanks 